Quotient Clinical Wins Three OncoADME Contracts

Quotient Clinical has been awarded three contracts for OncoADME programs to support clinical mass balance/ADME investigations in cancer patients. Two of the programs are for U.S.-based biopharma organizations and the third is for a top 10 global pharmaceutical company.
 
Quotient’s OncoADME service employs the company’s real-time adaptive manufacturing approach to supply ¹⁴C radiolabelled drug products to specialist oncology clinics globally. Drug products are manufactured on a ‘per patient’ basis and supplied to the clinic for dosing within two weeks of patient enrolment. This approach tailors drug product manufacturing to patient recruitment and aims to reduce overall project costs and enable the management and control of any issues related to instability of the ¹⁴C radiolabel.
 
Mark Egerton, chief executive officer of Quotient Clinical, said, “We are extremely pleased with how the OncoADME service has been accepted by our customers. Our ability to manufacture drug products in real time, and synchronize manufacturing activities with patient recruitment, is proving an effective way of reducing drug development costs and improving efficiency. Over recent years we have become one of the leading global providers of human ADME programs in healthy volunteers, and we are now able to offer oncology drug development teams the option to undertake these investigations directly in cancer patients.”